To cheat on your girlfriend and have sex with another woman.
John: Yo, Jimmy's legit and grabbed another slice of pie at the party last night.
Fabio: Fuck ya. Grabbin another slice of pie is the shit.
Adjective
To be a big deal; very important, or popular
“Hey dad have you ever heard of the singer Elton John?” “Yeah he was a huge slice of pie back in my day.”