When a womans booty is noticeably big.
Joe:Damn look at that girls hot ass!
Sean: Yeah man her ass takes the cake!
Joe: Nah bro, her ass takes the whole bakery!
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When somebody does something so idiotic, in the greatest of ways, what was done was so stupid, there is no comparison in known history, to say someone else did something more idiotic.
Doctor: "I've seen a lot of guys hurt themselves in stupid ways in my day, but yours takes the retard cake!"
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They want you to stick it in their booty.
"Brad, literally just take my cake already."