If one knows what's up - they got it, have it figured out, the one you can trust in the specific situation they're the one to follow.
*someone talking about politics and solidarity on the telly* yeah, he knows what's up!
Getting pegged with a carrot and then having your partner take a bite out of it explaining “Eh, what’s up Doc?”
Jessica brought a carrot into the bedroom last night. I knew instantly she wanted some What’s up Doc?
Something ONLY TEENAGERS say because If older people say it it’s NOT cool
Being so high that you send nonsensical things to people over text.
Dude guys, I almost sent "what up Smith Jones" to my aunt!
No lies, no cap, only real, real friends, real truth, real life, Real true friend. That’s mad what up
That’s mad what up bro
A form of speaking to someone, out side of saying hello.
POV: someone calls your phone…
You Answer: What up Doe so and so.
The act of taking a huge dab to become really high
Hey man, what do you say we go say what up to John after church?