A physical malformation resulting from the over-consumption of the popular party drug mef, or "mefamphetamine."
If you don't lay off the mef, you're gonna get da mef mouf.
When a methhead does something f'd up. (or messed up)
Meth-heads by nature have nil, or at best, limited teeth left.
Hence the pronunciation of "Meffed Up".
Can be used to describe a person's appearance, or an egregious situation, the term can be used quite broadly and still remain effective in meaning.
Did you see that lady back there... (grimaces/smirks) "Dude, she was all meffed up!!"
a mixture off miffed and pissed off, so therefore annoyed
Duncan was meffed off that the girl he was in love with continued to refer to him as her GBF.
4👍 1👎
The euphoric state one finds them self in after consuming copious amounts of methamphetamine with their Bestie.
Ali and his Freemasons must’ve hocked their holes at the traino because they’ve got the big bag and they are extremely fucking meffed