The big leagues, specifically the MLB.
Sanchez isn't ready for the bigs, yet.
In a sorority or fraternity, a big is given to an individual who is then a little.
What your mom always says to me when she sees this Dick!
Damn Leo, your cock is pretty big ,hopefully it's going to fit!
When playing Super mario brothers and mario is big.
Darn it i just lost my bigness,
That stupid turtle just killed my bigness.
No! Lookit that BIG-BIG!! Who lied to you and said you could wear that spandex???