When something feels off about a place, person, thing, event, etc.
When a person is acting very out of character, or is so out of their mind fucked up on a combo of drugs that they are not able to properly function.
Fuck bio one: Damn, did you see Slut Monkey last night? She dropped some E, drank a 5th, and slammed back three Redbulls! Bitch was straight Fuckey!
Fuck boi two: Man, that whole party was Fuckey!