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It was first said in the Golden Girls season 7 episode 19 and to get in a good laugh you mention something to do with Joe and they'll ask "who's Joe" and then you scream "JOE MAMA" and then everybody laughs
Person: god this food is delicious
You: oh man Joe would love this
Person: Whos Joe
You: JOE MAMA HAHAHAHAHA
<I heard Joe made it onto the Basketball team?> <Who’s Joe?>
<JOE MAMA!!!!!!!!> <BOOM ROASTED!!!!!!!>
Joe mama with anotha father and ur uncle beating you to go to school...
Person 1: Hi Joe!
Person 2: Who's Joe?
Person 1: Joe Mama
Person 2: ...
"I met joe today." "Joe who?" JOE MAMA IMAO BOOMER XD
A popular internet troll where somebody mentions the name 'Joe' and the other person may ask who joe is and the troller would answer 'Joe mama'. It is supposed to sound like 'your/yo mama'.
Derick: "hey Candice I got a new girlfriend their name is Joe"
Candice: "Who is Joe?"
Derick: "Joe mama"