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A more polite way of saying "holy shit". If you will, or if you're religious, it's a good way to express shock, or disbelief without being sent straight to hell, or the Headmaster.
Girl 1: *Squee!!* i got tickets to the MIKA concert! 8D
Girl 2: Ho shizz, you're kidding!! 8D
any corpse turned trick, by jeffrey dahmer, before the authorities can match dental records.
mr. dahmer licked his fingers and belched as he finished turning out, another john doe ho. the best part was he got his money back and a full belly everytime!
When a woman has intercourse with two different men in a short period of time resulting in fraternal / superfucundational twins being born - often of different races or color.
LaQuesha got fucked by both Darnell and Chad at the club last night - now she is expecting Ho Twins
When a person puts on so much makeup, it looks caked on, Usually involving a ho.
Bro did you see that ho-cake over there?
Typically a co-worker with no innovation while carrying out their tasks. Someone happy with the status quo with no thoughts about how to improve.
"How was Greg's presentation?"
"How do you think? That ho hum mother fucker hasn't changed it in years!"
To treat a woman like a whore sexually. Specifically to get her to do things you wouldn't want your wife of GF to do.
Hey man can I get with Krissy tonight ?
Sure, after I ho her out she's all yours.