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peaking on LSD and tweaking on methamphetamine simultaneously. Being under the influence of speed and acid at the same time.
Dude, I was puh-tweakin' hard all last week! Those were some fresh doses!
Your crew or your boys are acting out or being foolish. Your boys are tweakin and needa chill out.
Don: aye, Ern over there actin a fool
Boat: yea I know! what the hell is he doin?
Don: Foenem Tweakin’ for real brother
From Bobby Shmurdas "Hot Nigga". Tweaking is a movement where you move your knees back and forth and you move your hands to your chest back and forth.
"and now we tweakin hoe"
Omg call Karon, she’s driving down the gravel road with her tweakin beacon on again. That bright headlamp is a sure way to catch a case at 3a.m.
when a person is paranoid while being angry at the same time
Bobo was trip-tweakin earlier yelling at everybody bout the undercover laws in the woods
a meth head or crack head also know as a tweaker that stands on the roof and trys to land airplane's/UFOs
noah:bro what that guy doin trying to land a pound of meth
brad:hes a tweakin-beakin man
It basically means you're off the shits, your under the influence of something, for example, Molly, or anything in that range
"Tell guwop that you're tweakin and geekin -"( Cheech and Chong) by Gucci Mane