Four by four

It's a sexual move involving for people as shown on SNL. It involves you, you, me, him, you

Let's make a plan, how you want us to do this with you two? You want us to do you one by one, two by two, two by three or four by four

four by four

A woman who has had four kids by four different men. Generally considered to be bit of a hoe or slut

John: That Kate still looks hot for 40. Should I take her out?
Tom: Wow mate, I'd stay well clear of her, she's a four by four.

Fours (four fingers up)

Feel homosexual

Throw up the fours (four fingers up)