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basically means..Shit my Nigga..
all the other definitions 4 it on ere are wrong..
keisha: omg jason just got robbed!
jemal: shizzle my nizzle..lets kick yard an tell his brother
To force someone to pay the money they owe you.
Mike:Shawn, isn't dat ur ho?
Shawn:Yeah, hey ho, shizzle-ma-nizzle!!
This is a verb. To shizzle my nizzle means to take a salt shaker (aka shizzle) and have it expel its sodium-rich innards over someone's belly button. (aka navel, which leads to nizzle.) Shizzling someone's nizzle is a great sign of respect in many countries. Just don't do it in Italy. Ho boy... trust me.
He shook hands then shizzled my nizzle.
Read backround written by Weeabix. But can also mean "for sure, my nizzle"
"Can i hav a puff?"
"Fo' shizzle ma nizzle!"
a bastardization of "fo' sheezy mah neezy" which is a bastardization of "for sure mah nigga" which is a bastdardization of "I concur with you whole heartedly my African american brother."
"fo shizzle ma nizzle that is dank shit"