42

Everything.

42.

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42

According to Biblical genealogies found in the gospels there are 42 generations between Abraham and Jesus. Christians contend that Jesus is the answer to 'the Ultimate Question of Life, the Universe, and Everything'.

42 could be considered an example of truth being stranger than fiction*.

*Or possibly just an interesting co-incidence.

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42

The number of dead kids in my basement

Me: *Puts in 42, expecting "hitchiker's guide to the galaxy" jokes*
Urban Dictionary: *gives me 420 jokes instead*
Me: What the fuck??

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42-42-564

Whenever you need him, knock on death's door

Soul Eater, Episode 1 - Resonance of the Soul...

Maka: "The number to the death room is... 42-42-564 (shini shini koroshi)

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42

In addition to be the Ultimate answer to the ultimate question of the meaning of life, the universe and everything, it is also short hand to refer to 'Life, the Universe, and Everything.'

As in "How's your 42?" or "What's new in your 42?"
Or even "Never mind what my 20 is, where in the 42 are you?"

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42

stands for fuck me

Hey wanna 42?

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42

The answer to everything.

A: What is the definition of everything?
B:42.
A:Ok,Thanks.