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When you are a fairly attractive person but you can't seem to maintain a relationship regardless of how attractive you are.
SUE: My boyfriend broke up with me. I thought we had a great relationship. I don't understand why I can't manage to stay in a good relationship.
LORI: Girl...you got Jennifer Aniston Syndrome.
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A really great actress, a truly beautiful lady, and deserves more than given.
Tris: Jennifer, will you marry me?
Jennifer Aniston: Sure.
Tris: Wahoo! Screw you Brad Pitt!
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Not wearing a bra with your shirt or dress.
look at that skank over there
she's hot, but she's totally pulling a Jennifer Aniston
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Award winning actress, executive producer, director, and a absolute queen
Oh look it’s SAG award winner Jennifer Aniston
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She is perfection. Every room she walks into she fills it with light, joy, and happiness. Her smile is everything <3
“Jennifer Aniston truly is America’s Sweetheart...”
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Jennifer Aniston (born February 11, 1969) is an Emmy and Golden Globe Award-winning American film and television actress, best known for her role as Rachel Green in the popular television sitcom Friends. Since Friends she has starred in several successful Hollywood films, including Bruce Almighty, Along Came Polly and The Break-Up.
For the last three years a victim of lunatic Holy Jolie fans from a gossip blog.
Beautiful, talented and smart, she causes Brangaloonies to convulse.
At the mention of Jennifer Anistons name, the Brangaloon stuck her thumb in her mouth, dropped to the floor and started screaming.
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A compliment one pays to his wife or girlfriend, especially as they approach a more mature age. Meaning she is as hot if not hotter than Jennifer Aniston (circa: Just Go With It bikini scene)
Husband telling his wife: "Fuck Jennifer Aniston, I'd rather sleep with you!"