A strong urge have sex with a lot of different people and sail the ocean blue while you are in a long term relationship with somebody.
Dad: What happened to Jack and Jill? They have been together for 10 years!
Mom: Well, after Jack came down the hill with a pail of water, he decided to leave Jill to sail the ocean blue. When Jack came back, he came back with the clap and a boatload of crabs.
Dad: Yea, I remember when I came back from having the Christopher Columbus Syndrome. I gave you syphilis. I think I still got it now that I mention it. Don't tell the kids.
Mom: Those were the days, good times.
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When you take a shit and leave it for the next person to discover it
I had to poop so bad in the Waffle House. When I walked in there was a Christopher Columbus starring at me!
When you go to the bathroom in another department at work to leave the vilest shit possible.
I had to go over to General Assembly to get some parts and Christopher Columbus'd while I was there.