It's like the expression, "don't get your panties in a bunch." Literal meaning is to not get worked up.
Just because I slept with your sister, don't get your twat in a knot.
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This knot was discovered in the Lawn Care industry of western Pennsylvania for securing equipment on a trailer. The knot is comprised of three inter-locking loops to tighten the slack out of the line and two slip knots (know as the double back rocket) securing the locked loops. This is a very secure, but easy knot to untie when access to the secured object is needed frequently.
We have a long ride from Moon to the Rochester Beaver run, you better tie the Triple Lock-Knot Double Back Rocket to secure the walk behinds.
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When a girl is giving anal while performing a 69 with two guys both with hooked/curved dicks
Girl 1: I got into a double fisherman knot last night. It was intense!
Girl2: I always wanted to try one of those!
A butthole on a person or animal.
Tommy and Johnny like to tickle each other in the Ballon Knot
Basically being dicked down by a furry.
Person 1: Hey you wanna get Knotted Down?
Person 2: Sure, I always wanted to get Knotted Down!