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Mayo is slang for the word Mayonnaise, a.k.a. the greatest food to ever exist, if you do not eat this, you have problems
John: Holy Crap I love mayo!
Sam: How can you love mayo, it sucks.
John: WTF is wrong with you Sam, are you retarded.
a not talented girl that lets all good dancers disappear behind her. wow it's magic
also known as burger
"Did you see that crutsy dusty mafxckin lookin fat a** diabetes bicth at the Chizuru? Yeah thats mayo."
Think about what mayonnaise looks like if you let it sit outside a fridge for a couple weeks.
Person 1: I found this old sock by a dumpster and it looked crusty.
Person 2: Eww bro it probably had street mayo in it.
A Trans women with yeast infection
Someone who leaves their tuck friendly underwear on for too long Spicy Mayo