Portmanteau of "irrespective" and "regardless", likely used mistakenly rather than deliberately. While technically this could be a meaningful term directly, due to the double negative of ir- and -less this would make this mean the opposite of the terms that form it, which is never the intent when used.
a lot of people hate it, but people use this term irregardless
Used to emphasize, or build upon the solid structure of the word(irregardless) a further mutilation or the root (regardless)
He couldnt believe he was there. Irregardlessness of his intention.