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Duff

A blonde chicks vagina.

"Hillary's duff"
"Go get you some of that duff over there"
"I bet that chick has a nice duff"

by Fagboyslim88 January 13, 2017


Duff

Designated-ugly-fugly-friend
The one friend in the group who doesn’t really feel like a friend Becuase of how irrelevant they are or feel and when in public is the one who gets asked for the phone numbers of the other attractive friends.

“Yoo you see those hella fine girls man”

“ yes sir I do”

“Go see if you can get their numbers”
“ nahh I’m too pussy”
“Oh fairs, jus go ask the DUFF then, their there for a reason”

by Doorknobsontoast_420 July 11, 2020


Duff

The brand of beer that Homer drinks in the Simpsons.

Duffman approves this definition

by kunemvu February 24, 2020


Duff

Beer you wish you could have but never will.

I'm craving some duff right now bro.

by lemonberrypie August 4, 2017


duff

The stuff left on the bottom of your weed bags. All the stems, crystals, and leafs. Often used as a cheaper alternative to buds in baking. Though often mistaken as good, and used in joints and bowls. Known to be sold for as cheap as 30-40 dollars an ounce.

Hey bro, got any of that duff? I need to make another's batch of weed brownies.

by fitzy_keegs December 21, 2016


duff

dumb ugly fat friend

"cant she see she is the duff"

by go to bed April 19, 2017


Duff

A cocktail consisting of equal parts Cynar, Campari, and gin with a splash of soda and an orange twist.

"Hey bartender, I'd like a drink that's neither too sweet not too bitter."
" How about a Duff?"
"Perfect!"

by megadope September 21, 2023