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Lean Mass Hyper-Responder

The term "lean mass hyper-responder" was coined by software engineer David Feldman on July 3, 2017 while posting in his low-carb diet blog: "Cholesterol Code." The blog post called "Are you a Lean Mass Hyper-responder?" quickly circulated through the low-carb community.

As background, the original term "hyper-responder" was already used by dietary professionals for years prior to Feldman's blog post. And in dietary literature, a "hyper-responder" is someone who adopts a low-carb diet, then experiences dramatic cholesterol elevation. So when Feldman wrote his 2017 blog article, he co-opted "hyper-responder," and crafted his new term "lean mass hyper-responder" to describe what he believes is a metabolically unique sub-set of all hyper-responders. Specifically, some hyper-responders begin a low-carb diet while already in possession of a very lean body mass. And yet in spite of this, they still --quite counter-intuitively-- respond with extreme cholesterol elevation. Additionally, these subjects experience a marked decrease in triglycerides, while exhibiting excellent metabolic health. The entire phenomenon defied a long-standing metabolic theory called "The Lipid Energy Model," presenting a scientific conundrum for Feldman.

Feldman believed that all this was a significant observation worth exploring. And his efforts eventually led to a 2023 research project called "The Lean Mass Hyper-Responder Study" led by Dr. Matthew Budoff and Dr. Nicholas Norwitz at Lundquist, UCLA.

IN A SENTENCE: "Steve has always been a tall, skinny, beanpole of a guy. And then when he went on the carnivore diet, he was still skinny, but his cholesterol went through the roof. His doc said that overall he's pretty healthy, so he might just be a lean mass hyper-responder."

by Innocent Byproduct December 13, 2023


Lean Love

See: Skinny Love

(Primarily used:1970s)
Largely popularized by the English rock band T. Rex in the song Lean Woman Blues. It was track 5 on the album Electric Warrior, the bands 2nd studio album as T Rex. (Formerly Tyrannosaurus Rex)

Oh, lean love. All you give to me is your lean love.

by psychonerderer June 19, 2023


heavy lean

When you are so drunk you are leaning on anything you can find or can manage you.

I was so drunk I was doing the heavy lean on the table, counter and walls.

by We have all been there August 13, 2022


Jonnie Lean in

Whilst playing table tennis a server will lean over the table in an attempt to gain a greater angle whilst serving the ball.

Warren completed a Jonnie Lean in to get a greater advantage whilst serving.

by The Rough December 3, 2013


Lost on Lean

Lost on Lean is still UCL Myth no matter what he decides to change his name too.

PS. stupid bitch.

Ayo Pierre tell Lost on Lean to get his butch ass on, we late.
Kinda a real nigga but still goofy and probably will always be into fat bitches.

by MythsCousin December 7, 2021


Lean pill

Accepting the fact that being lean (<=15% body fat) is optimal for male health and attractiveness. A person who believes this is said to be lean pilled.

This belief exists to counter the narrative pushed by powerlifters and perma bulkers, which states that one should just get as big as possible and prioritize lifting numbers above everything else.

Friend: What happened to you? You used to be so strong and swole!
Me: I decided that feeling and looking my best is better than being able to bench 4 plates. I took the lean pill.

by OW_player June 12, 2024


lean position

Military slang for getting bent over or fucked in the work place. usually by an officer or over eager senior NCO.

"ok people, i know were supposed to head home from the desert tomorrow, but if we do another 2 months we can all get a short tour ribbon and i dont have one yet!"

from the crowd "Lean position ho!!!!!!!!!"

by William Burkhalter May 7, 2008