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condition you experience after a long night when you have taken any combination of mind or state altering substances
wisdom teeth removed= percocet+ free beer night at bar= combo buzz
A powerful weapon combo in the hit Xbox game, Halo 2. To perform it, a player finds a Plasma Pistol and Battle Rifle, takes them, charges the Plasma Pistol and fires off a shot at the opponent, instantly making the target lose their shield. Then the player needs only to switch to the Battle Rifle and fire off one shot to the head (or two shots to the body) to get an instant kill on the target.
It is widely used in maps like Colossus and Beaver Creek. Do not judge the combo by its widely-used name, however. It takes skill to some extent to aim the Battle Rifle in the right spot.
Player 1: How did you get 40 kills, Player 2?
Player 2: Noob combo, biyatch.
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To perform oral sex on the vaginal and anal region of a woman alternately while she is on her hands and knees.
Robert: I’m starving.
Betty: How about a combo platter?!
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When you throw someone at less than 40% in Smash and you don't combo them after
HopCat just did a HopCat Combo
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A newly created term associated with the game Dungeon Fighter Online, or DFO, in which one player (in PVP) strings together so many attacks in a row that the opposing player has enough time to make a sandwich, eat it, and come back before the combo is finished.
Seth: I'm kind of hungry.
Paul: Well here's your chance. Looks like this is going to be another sandwich combo.
Seth: Great.
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A chick with legs, thighs, and breast.
That chick is a KFC Combo!
When you're fucking your girl and you catch her by surprise with a finger in the asshole, a tug of the nipple, and a bite to her neck.
"Dude, I'm going to Jennifer's tonight and I'm definitely gonna combo that shit!"