Inside Out

A girl tries way too hard to be happy all the time and gets really damn depressed. Sadness ensues. Get the tissues.

Person 1: "How dead inside are you?"

Person 2: "I didn't cry watching the movie Inside Out."

Person 1: "Damn. Me too. We're both practically walking skeletons."

Inside-Out

When someone has been on the toilet for so long that they've almost flipped "Inside-Out" due to how much pushing out of poop they must have done.

David: You were in the toilet for a long time!
Bob: So sorry, I think I ate something bad earlier.
David: We all though that you had flipped inside-out by now!