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Also known as Trisomy 21. With 23 pairs of chromosomes, a person with Down Syndrome (i.e., a retard) has an extra 21st chromosome, causing several physical and mental defects. Usually easily recognized due to the retarded shape of their face and the clueless, happy expression on their face. These poor brain-dead sacks of sweaty garbage might be able to hold down a job as a greeter at Walmart, but this is about as high up the corporate ladder that these circus freaks typically go.
"Oh my god, did you see that dipshit window-licker trying to parallel park a shopping cart? What a down syndrome, fat fucking gay retard, fucking just dumbass stupid fucking loser. Let's kill him. I'll drown his ass, what a fucking puke piece of shit."
when you have all the chromosones
Yea Nathan have down syndrome
Someone with an extra chromosome
He liking his balls i think he has Down syndrome
cody zinkus down syndrome
cody zinkus looks like a sped down syndrome
A retarted ass dog named duke that has 3 missing chromosomes and likes dick up his ass and having cats shoved up his ass
Person 1 : how’s down syndrome
Person 2 : he’s not Down syndrome it’s fucking duke