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A person who is experienced in eating spicy foods, specifically Hot Peppers or sauces that incorporate high potency Capsaicin.
Wow, Pat really took those Ghost Pepper wings to the face, they must be a real Spice Lord!
Usually followed by the rubbing of the thumb, index, and middle finger. "That's spice" is used when something is cool or an action is executed perfectly. Using this with your friends will immediately turn you into a group of faggotoni pepperonis.
"Watch me sink this half court shot," "Bet!" *Sinks shot* "That's spiceeeeee"