Weird sex act of beating your meat
Big O likes to get his fingers loose
a pair of socks which are clearly not intended to be worn together.
Ted struggles to find an appropriate clothing for his feet. Fearing he may need to wear dirty socks to work, he clasps two loose brothers together and pulls them onto his suspiciously large feet.
A phrase used to describe a woman with huge hanging boobs.
Woman 1: Dude, did you see those F's on the loose?
Woman 2: Yea, they were huge.
Woman 1: It was like two watermelons were hanging from her chest.
Woman 2: But even with those things she was ugly as hell.
Woman 1: Yea, totally.
meaning you turnt or feeling relaxed
*dior starts twerking*
her friend: OOOH GIRL YOU BEEN TOO LOOSE OOOH YOU LOOSE OH OH OH YOU LOOSE
or
dior: *starts a live video* y’all i am too looseeeeee right now i’m finna fall asleep real bad.
A woman getting married that has slept with a 3 or more men that were in attendance at her wedding.
Non-virgin man1: Did you see Tara at her wedding? I felt pretty awkward seeing her get married to billybobjubilous.
Non-virgin man2,3, and 4: Yeah she's a bit of a loose bride.
A person, often holding a position of significant responsibility within military, political, or business contexts whose words or actions are considered by some to undermine established objectives of the greater organization.
In our operations handbook, the section with the heading "definitive loose cannon" contains a picture of John Bolton.