When someone totally loses their shit on you and and you are incapable of dealing with it
Man that woman was going schizo on me when I asked her about whose number that was.
Needing to go to the toilet right now, insomuch that it is a life or death situation
"Mum, are we there yet? I'm dying to go!"
"Not far honey. We should probably buy a Happy Meal or something so we don't get into trouble."
Consuming abnormally large amounts of nutmeg to obtain a cannabinoid/deliriant high
I've been going nuts for so long my wife left me when I thought her foot was my sounding tool
When a man cums like crazy.
Hobo 1: Bro look at that bitch. I am going nuts.
Hobo 2: Creep
Alternative use of the phrase "go big or go home"
Schould not be used in family friendly matters
Family Friendly: If you go on the treadmill, go big or go home. *falls off treadmill" i guess i'll go home then.
Alternative: If you go on the treadmill, go big or suck dick. *falls off treadmill" ...