1.When you take one big ass bite of your Wendy's T-Rex Burger violantly and out of a spontaneusly action often influenced by extreme munchies.
2. Or: You are a famous boxer who is influenced by an excessive use of cocaine ...and bite of a chunk of your opponents ear.
1. "Yoo Stephen don't you look at my burger like you bout to take a Mike Tyson Bite of it!"
2. "Damn this dude must be hungry af when he starts eating goddamn ears! That was one nasty Mike Tyson Bite."
When a girls sucking your dick you punch her in the back of the head and say "Mike Tyson".
I gave her the Mike Tyson
If your friend falls asleep at a party and you just leave them behind without saying goodbye.
In distinction to a french exit where you just sneak out of a party without telling anyone, "to do a Mike Tyson" specifically means leaving the person you came together to the party behind, because he/she fell asleep there.
How could you just do a Mike Tyson last night? I woke up next to these bunch of strangers in the middle of the night and had no idea where you are?!!