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An anime originated term used to describe when a female side character with more character development than a main female character whom both show affection/ love interest to a main lead (usually male). The side character ends up building a lot of attention and cheering for her and her interest. The effect ends with the side character having her feelings rejected by the Main lead.
"Hey dude, what did you think of Ana? I hope she ends up with Taichi and isn't shut down by the Rem Effect."
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The knowledge of impending doom caused by the conclusion of the Mayan calendar and feeling like everything is going to be fine.
Jack: It's the end of the world as we know it. And I feel fine.
Jim: He's suffering from REM Syndrome
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best admin in the whole server and maybe the best admin in the whole world :D
rem your bedroom is good and best admin
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who?
like im not kidding who is this Rem?
weeb: you know rem from Re: Zero?
human: no who is that?
weeb: *having a panic attack*
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Latin for "go to the bad place", which translates as "go to hell". The Romans considered it unlucky to name the bad place.
ii in malum rem, you fracktard!
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best underground artist onb
u heard dat new rem aka thraxpaxkrem?
nah who df is rem
..
*blocked*