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The listless state of consciousness experienced after eating a KFC Double Down sandwich.
Brad: "Why does Ken look like he's about to collapse?"
Trevor: "Judging by the lunch we just ate, it is my determination that Ken is suffering from Double Down Syndrome."
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A person who cannot get off fortnite. If they do they will crave it until they get back on. Some call it Fortnite down syndrome, others call it being 9 years old. What ever It is I have it.
Bro my little brother wont get off fortnite!
Yeah I saw, I think he has Fortnite down syndrome!
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When some one is acting like and autisticcancer ball
Tom hanks has depression and upside-down syndrome
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A semi-uncommon disorder among Mexican immigrants, MDS consists of a total lack of knowledge of American culture and language. Phrases such as "Come over, i'll cook you", "I love the smell of burn", "Can I use powerful words?", and "Smelt" are used frequently. Patients diagnosed normally don't have many friends, and are give shit by nearly everyone.
Jay: Did Rosa just say,"Shit my hole"?
Matt: Give her a break, her doctor says she has a case of chronic Mexican Down Syndrome.
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aliens with down syndrome, that usually live in people's vagina's, preferrably mine
When I run, the down-syndrome aliens fall out of my vagina
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1. An epidemic sweeping the nation causing puppys eyeballs to grow farther apart, thus allowing the brain to push forward in the vacant space, causing retardation.
2. Something to laugh at when at a party.
-Dude, why does your dog keep humping my leg?
-Oh Captain Foogles there has puppy downs syndrome.
-Hahaha.... Oh you're serious?
-It's an epidemic.
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A retard with down-syndrome abilities.
Down syndrome defenders are so fat they cant be hurt.a
Arham is such an obese down syndrome defender!