Originating from the phase, “what the fucks the matter with you”, Ahyou is a word you whip out when you wanna ask someone what’s wrong with them. Can also be said as; “AHYOUUU” or simply “you?”.
Friend 1: Yo man I was so trashed last night that I climbed a building and threw a ladder off of it”
Friend 2: AHYOUUUU