Awe piele is a phrase used by South Africans who typically live in the western cape. It consists of the combination of the two Afrikaans words: "awe" and "piele".
This phrase can be, and is used in almost any context, but it is mostly used: during a greeting, in response to a question (where "awe piele" would replace the word "yes") and it is often used as a way of showing of excitement or that you agree with a statement.
In response to a question, and an exclamation of excitement:
John: Patrick, are we still going to braai tonight?
Patrick: Awe piele!
As a greeting:
John: Jus Patrick.
Patrick: Awe Piele!
In agreement:
John: Should we take a smoke break?
Patrick: Awe piele.