Adjective: Egregiously horrible circumstance or feeling.
Noun: A disease in which there is a severe loss of the body's cellular immunity, greatly lowering the resistance to infection and malignancy...but in ones balls.
Adjective: He watched his dad get hit by a bus. Talk about a ball-aids day!
Noun: Don't mess around with those crazy rich Asians. That's how you get the ball aids.