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Dirty Francesco is the act of making a hole in the pillow, drawing your best friend's face on it, then penetrating it until it is filled with semen and then drinking the semen from the pillow
I have to go buy another pillow because I made mine the "Dirty Francesco" and it no longer works
To make a girl overdose on Xanax during a party, kiss her and try to have sex with her.
Guy 1: “Dude, that girl is so cute I might pull a dirty Francesco on her”
Guy 2: “Here, have my Xanax pills”