It's a cruel name for an elderly person that just made you extremely angry
Old Guy(Bus Driver): You guys better stop yelling and moving seat to seat or I'm gonna stop this bus
Angered Teenager: Shut the fuck up you Dusty Ass Bitch!
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Person one: Hiii
Person two: STFU YOU UGLY MUSTY CRUSTY FUGLY DUSTY ASS BITCH
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A derogatory term for wrestlers in the MMA world. They always shoot for a takedown at the earliest opportunity. Fucking annoying.
He hurt him! HE HURT HIM! No one saw it! That's why he shot for a takedown! Dusty ass bitch!