A "C" note. Heard this expression once, many years ago, in Louisiana, believe it was a localized Creole slang. May have read it in the comments section of WorldStar Hip Hop web site.
I presume that "titty" refers to the extra zero a hundred dollar bill would have, that extra zero standing for a rough cartoon version of a female breast, nipple or areola.
Reverend Ike, admonishing his audience to give generously: "I don't want no twenty dollar bill! I don't want no fitty dollar bill either! Pull out that fitty wit a titty—a hundred dollar bill—that's what I want to see!