A heterosexual female or homosexual male who is both obese and promiscuous. “Five guys” refers to the servicing of many men, and “burgers and fries” refers to all the fatty food they eat.
Brenda really makes the rounds whenever she’s not stuffing down cheese and charcuterie plates. She’s no stranger to the biscuit tin and no stranger to the sausage bin. Five guys burgers and fries!