Becoming fully, truly, unstoppably, gravitationally angry. Usually of a person or semi-sentient animal that can experience anger.
References ballistic missiles, whose flight paths are nearly un-alterable after a certain point.
"When dad finds out I didn't submit my college applications, he'll be going ballistic!"
Get very angry, such that you lose your self-control.
I wouldn't start by telling her that you actually slept with Rachel. She'd go ballistic and you'd never be able to explain the rest.
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Getting so angry that you literally launch yourself up like a ballistic missile
Wesley: Hey man, how's John doing now?
William: I don't think he's alright, he's going ballistic after his girlfriend left him.