A hennyloko shotty is when you shotgun a hennyloko, typically resulting in a great night.
A hennyloko is a drink that consists of the combination of Hennessy and a Four Loko. To make a hennyloko, pour 5 shots of Hennessy into a Four Loko.
Bro 1: "Yoooo brooo lets rip a Hennyloko Shotty!!"
Bro 2: "YO type shit bro that'd be so hard!"
*bros shotgun their Hennyloko Shotty"