The very first recorded blossoming of sores on an individual (either orally, genitally, anally, or elsewhere on the human body) as caused by the herpes virus.
Todd: Sam, it looks as though I've got a pretty bad sore down there. Do you have any clue as to what it might be?
Sam: Why, Todd, that appears to be a case of genital herpes! This must be your first outbreak; in which case, Herpe Birthday, my friend!