Very commonly used and inconspicuous excuse for getting out of pretty much anything. One can replace the word 'brother' with any relative that would make sense. Possible substitutes include but are not limited to:
Sister, Cousin, Nephew, Niece, etc.
(Guy 1) Hey Guy 2, wanna hang out?
(Guy 2) One sec... Nah, I have to take my brother to baseball practice.
(Guy 1) Hey Guy 2, wanna see a movie with some friends?
(Guy 2) Can't tonight, I have to take my brother to baseball practice.
(Guy 1) Hey Guy 2, wanna play some football today?
(Guy 2) Sorry man, I can't play today. I have to take my brother to baseball practice.
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