A particularly unpleasant hangover.
"Last night was great, but I have the worst case of the irish flu today."
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An unpleasant hangover (From the movie "The Shallows"
" ...and now she's just stuck back at Las Rocas with the Irish flu"
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The ailment one suffers on March 18th after properlyly celebrating St. Patrick's Day. Anyone of Irish descent may also use the term to denote a hangover on any day of the year.
Seamus: Ugh, I was out drinking Guinness until the wee hours. I think I'll call in with the Irish Flu today.
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A hangover, usually involving whiskey; may be mild or severe
"I’ve still got a touch of the Irish flu."
"The Irish flu?"
"Also known as a hangover."
(from "A Nose for Murder" by Lee Charles Kelley
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