1. It means "queen" in the dothraki language. Usually the wrong-given name to Daenerys Targaryen, character from "A song of ice and fire" books (Game of Thrones).
2. Badass sexy girl who has dragons and says "dracarys" to her enemies and burns them all. She gets the things she wants with fire and blood.
I'm not a princess, I'm a khaleesi
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Queen Daenerys I Targaryen is the younger sister of Rhaegar Targaryen and Viserys Targaryen, the paternal aunt of Jon Snow, and the youngest child of King Aerys II Targaryen and Queen Rhaella Targaryen, who were both ousted from the Iron Throne during Robert Baratheon's rebellion.
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A perfect arse
An arse that defies gravity
Not too big, not too small, not flat, perfectly round
She has a khaleesi Keister
Having diarrhea of the mouth, being fake and/or phony and suffering from hallucinations.
"That bitch over there is suffering from Khaleesi disorder!"
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