Another way to say "pound it." A form of high-five when two participates pound their fists together, lightly, in celabration or greeting.
"That was a good one! Knuck up, man."
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What you say when you fist pound someone after they say something absolutely great
-derived from the term "gimme some knucks" (as in knuckles)
created by a freshman at Grafton High School '09
"Yo I got mad booty last night with this chick I've never met, it was great!"
"Knuck shit up to that brotha!"