Main vain refers to a penis. A mans main vain.
"dude, i gotta go drain the main vain" meaning he needs to urinate, piss.
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Also known as the penis. There is no muscle in the penis, the penis is erect by a massive rush of blood. Therefore another nickname for the penis is the Main Vain.
Don't use the brain, use the Main Vain!
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1. The act of releasing urine from your penis.
2. The act of releasing semen from your penis
I drained the main vain all over her.
Well, time to drain the main vain
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as in you need to go urinate(av a piss).
B: aw ive drunk too much. coming to drain the main vain?
C: yer sure...
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Snorting a white powdery substance off a fully torqued penis
did you hear about Leslie!? last weekend she was railing the main vain on a cruise ship and now shes married to a 65 year old millionaire.