a condition where a caucasian individual is only aquainted with one African-American person, and therefore feels every African-American person they encounter looks like said acquaintance.
White Guy 1: "Hey look that guy looks just like Marcus!!!"
White Guy 2: "Yea he does... kind of..."
White Guy 1: "Yea not really, I think its just because he's black. Must be the Marcus Syndrome."
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When someone has an insatiable addiction to Caucasian Females. They're willing to risk it all for some Caucasian Nyash, they'll even accept race play just to get a whiff of it.
Nate - "These Snowbunnies have me tripping dawg"
Marcus Edu - "Don't be ashamed, I've been doing this for years"
Morpheus - "Do you Believe in Marcus Edu Syndrome?"