When a guy who's professionally and financially successful dates or marries an ugly girl.
He makes six figures at a technology company but have you seen his girlfriend? She's fugly. He has a case of Mark Zuckerberg syndrome!
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When you force your political beliefs onto your website, and use your power as the founder to unfairly persecute those who disagree with you.
Mark Zuckerberg Syndrome be like:
"Howdy y'all, I'm Mark Zuckerberg."
"As you may know, I am a flaming liberal. If you're not, and I find out, YOU'RE GETTING KICKED OFF MY WEBSITE, YOU SON OF A BITCH!"
"....So anyway, I heard you were interested in toilets..."
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People that need someone else to live, survive and function normally.
Universities create these people that need people to do everythig for them, they have Mark Zuckerberg syndrome.