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A euphemism to the female body parts, specifically the vagina. First popularized on The Tonight Show by the fruitcake lady, who would offer bits of humor and advice to people, like a live "Ann Landers" column.
Woman, you ain't gettin' no sex tonight, because you don't keep Miss Puss clean!
A little miss stush puss is a girl that is vain and snobby they are usually like this when they are young from the age range of teens to late twenties
Wow that girl thinks she better than us she's a little miss stush puss