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A slang term for getting stabbed, shanked, or shived.
A fight broke out at the bar and I almost got a Mississippi Handshake!
When you cover your hand in shit and then give a sloppy handjob
Oh I just got the best Mississippi handshake from Dillon earlier
A sexual cosplay act involving five or more males and females performing an ancient Mayan rite of passage ritual with ghost pepper dildos.
I'll never forget my first Mayan Mississippi Handshake!