South Carolina ghetto slang for defecating oneself. Usually used in reference to the article of clothing soiled.
Damn it be funny when Shaquanda nanny up her underwear!
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Nanny up is a Gullah Geechee term that means to defecate, shit, poop, or to go number two. It’s mostly used when a child needs a diaper changed, but also if someone has used the restroom and has left a lingering odor.
“Which one uh dem chirren eh nanny up”
“Eh nanny up innuh bathroom”