Whenever something easy or undemanding is messed up or failed in an almost saddening, yet expected way.
Of course, in reference to the famous movie clip where Nico.
Dude 1 fucking dies choking on a cheese stick.
Dude 2. Wow, he really nico'd that one huh.
To binge a show, preferably an anime in one sitting at 1am, then not remembering anything, casusing a weak a viewing experience and not remembering anything after a day.
A: Beastars is really good.
B: Yeah I can't remember anything because I Nico'd it.