From "a pox on both your houses!" Only its you, you're having bad luck and lots of it. Like, if you keep getting sick, or you're in a fender bender and on the way to the mechanics you're in another you'd say, "Dude, I'm poxed."
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used in the manner of cursing someone, wish "a pox" on them, as in some sort of disease
"My lord, that man just drank the last bit of Ale..."
"A POX ON HIM"
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Bullshit (Marfia Bikes)
I ordered my Rocker BMX from Marfia over a fucking month ago, this is truly pox!
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